Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43198 | 0.95 | TSHR (0.61) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11311462 | 0.93 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8358973 | 0.93 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28929818 | 0.93 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL42087 | 0.91 | TSHR (0.67) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6783959 | 0.89 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL22471730 | 0.89 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21541953 | 0.89 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL22129975 | 0.89 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6791404 | 0.89 | TSHR (0.70) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516493-B2 | USE OF NETWORK COMPOSITIONS IN COSMETICS OR PERSONAL CARE PRODUCTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2022-11-16 | — | — | EP | claimed |