Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.56 |
| ▸ | BTK | Q06187 | 19/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23690726 | 0.92 | JAK3 (0.56) | JAK3BTKEGFR | |
| SCHEMBL23690859 | 0.84 | JAK3 (0.65) | JAK3BTKEGFR | |
| SCHEMBL23690782 | 0.82 | JAK3 (0.76) | JAK3BTKEGFR | |
| SCHEMBL23690779 | 0.82 | JAK3 (0.76) | JAK3BTKEGFR | |
| SCHEMBL23690781 | 0.82 | JAK3 (0.76) | JAK3BTKEGFR | |
| SCHEMBL23691109 | 0.81 | EGFR (0.55) | JAK3BTKEGFR | |
| SCHEMBL23690727 | 0.81 | JAK3 (0.72) | JAK3BTKEGFR | |
| SCHEMBL23690725 | 0.81 | JAK3 (0.72) | JAK3BTKEGFR | |
| SCHEMBL23690973 | 0.80 | JAK3 (0.66) | JAK3BTKEGFR | |
| SCHEMBL23690757 | 0.80 | JAK3 (0.62) | JAK3BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244055-B | Pyrimidine five-membered ring derivative and application thereof | 江苏先声药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-115244055-A | Pyrimido five-membered ring derivative and application thereof | 江苏先声药业有限公司 | 2022-10-25 | — | — | CN | disclosed |