Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K8 | P41279 | 19/20 | 1.00 |
| ▸ | MAPK13 | O15264 | 2/20 | 1.00 |
| ▸ | MAPK12 | P53778 | 2/20 | 1.00 |
| ▸ | MAPK11 | Q15759 | 2/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 2/20 | 1.00 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 1.00 |
| ▸ | SRC | P12931 | 2/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.62 |
| ▸ | PRKCG | P05129 | 1/20 | 0.62 |
| ▸ | PRKCB | P05771 | 1/20 | 0.62 |
| ▸ | PRKCA | P17252 | 1/20 | 0.62 |
| ▸ | PRKCH | P24723 | 1/20 | 0.62 |
| ▸ | PRKCI | P41743 | 1/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.62 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2369872 | 1.00 | MAP3K8 (1.00) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL30264449 | 1.00 | MAP3K8 (1.00) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5118168 | 0.92 | MAP3K8 (0.85) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5118384 | 0.92 | MAP3K8 (0.85) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4776035 | 0.91 | MAP3K8 (1.00) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL27730160 | 0.90 | MAP3K8 (0.85) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4904414 | 0.90 | MAP3K8 (0.82) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4963305 | 0.90 | MAP3K8 (0.83) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4766912 | 0.89 | MAP3K8 (0.79) | MAP3K8MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL4769727 | 0.88 | MAP3K8 (0.79) | MAP3K8MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230126310-A1 | COMPOSITIONS FOR CORONAVIRUS INFECTION TREATMENT AND/OR PREVENTION | FRAUNHOFER GES FORSCHUNG (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20220362329-A1 | TREATING ACUTE LIVER DISEASE WITH TLR-MIK INIHIBITORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-11-17 | — | — | US | disclosed |