Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23525972 | 1.00 | GRM5 (0.36) | GRM5PGRMGLLSOS1 | |
| SCHEMBL23525975 | 1.00 | GRM5 (0.36) | GRM5PGRMGLLSOS1 | |
| Hydrochloric Acid SCHEMBL31602980 | 0.98 | GRM5 (0.36) | GRM5PGRMGLLSOS1 | |
| Hydrochloric Acid SCHEMBL1006004 | 0.98 | GRM5 (0.36) | GRM5PGRMGLLSOS1 | |
| SCHEMBL23564081 | 0.84 | GRM5 (0.35) | GRM5PGR | |
| SCHEMBL12262985 | 0.84 | GRM5 (0.41) | GRM5PGRSOS1 | |
| SCHEMBL27868545 | 0.81 | GRM5 (0.36) | GRM5PGRSOS1 | |
| SCHEMBL26463822 | 0.81 | CYP11B1 (0.37) | GRM5PGRMGLLSOS1 | |
| SCHEMBL16958513 | 0.81 | GRM5 (0.36) | GRM5PGRSOS1 | |
| SCHEMBL25632952 | 0.80 | SOS1 (0.39) | GRM5PGRSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546304-A | Salts of SOS1 inhibitors | 米拉蒂治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| WO-2023240253-A2 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |