Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 7/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526345 | 1.00 | SOS1 (0.36) | SOS1PDE2AALKTRPV4CYP11B1 | |
| SCHEMBL23526343 | 1.00 | SOS1 (0.36) | SOS1PDE2AALKTRPV4CYP11B1 | |
| Hydrochloric Acid SCHEMBL30594974 | 0.98 | SOS1 (0.36) | SOS1PDE2AALKTRPV4 | |
| Hydrochloric Acid SCHEMBL29125254 | 0.98 | SOS1 (0.36) | SOS1PDE2AALKTRPV4 | |
| Hydrochloric Acid SCHEMBL29125255 | 0.98 | SOS1 (0.36) | SOS1PDE2AALKTRPV4 | |
| SCHEMBL23564026 | 0.87 | SOS1 (0.35) | SOS1ALKTRPV4CYP11B1CYP11B2 | |
| SCHEMBL25839061 | 0.85 | SOS1 (0.38) | SOS1ALKTRPV4CYP11B1CYP11B2 | |
| SCHEMBL23526352 | 0.84 | SOS1 (0.35) | SOS1PDE2AALKTRPV4CYP11B1 | |
| SCHEMBL29945727 | 0.84 | SOS1 (0.35) | SOS1PDE2AALKTRPV4CYP11B1 | |
| SCHEMBL23526350 | 0.84 | SOS1 (0.35) | SOS1PDE2AALKTRPV4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546304-A | Salts of SOS1 inhibitors | 米拉蒂治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |