SCHEMBL29946644

SCHEMBL29946644

CC(C)NC1[C@H]2COC[C@@H]12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18347914 1.00 BRD4 (0.30) BRD4
SCHEMBL4546672 0.72
SCHEMBL21870590 0.70
SCHEMBL24992207 0.70
SCHEMBL23714366 0.70
SCHEMBL24316142 0.69
SCHEMBL23170661 0.68 GBA1 (0.32)
SCHEMBL21890781 0.68
SCHEMBL21238477 0.67 BRD4 (0.35) BRD4
SCHEMBL18347960 0.67 BRD4 (0.35) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337203-A1 INHIBITORS OF THE MENIN-MLL INTERACTION Syndax Pharmaceuticals, Inc. (US) 2024-03-20 EP disclosed
WO-2022241265-A1 INHIBITORS OF THE MENIN-MLL INTERACTION SYNDAX PHARMACEUTICALS, INC. (US) 2022-11-17 WO disclosed