Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24981612 | 1.00 | MEN1 (0.39) | MEN1KMT2AKCNH2GRM5CYP1A2 | |
| SCHEMBL19693650 | 0.88 | MEN1 (0.46) | MEN1KMT2AKCNH2GRM5CYP1A2 | |
| SCHEMBL29946701 | 0.85 | KMT2A (0.34) | MEN1KMT2AKCNH2GPBAR1SCN8A | |
| SCHEMBL24981756 | 0.85 | KMT2A (0.42) | MEN1KMT2AKCNH2GPBAR1 | |
| SCHEMBL19693483 | 0.83 | MEN1 (0.48) | MEN1KMT2AKCNH2GRM5CYP1A2 | |
| SCHEMBL29519417 | 0.83 | MEN1 (0.48) | MEN1KMT2AKCNH2GRM5CYP1A2 | |
| SCHEMBL19694116 | 0.82 | MEN1 (0.40) | MEN1KMT2AKCNH2GRM5CYP1A2 | |
| SCHEMBL29519411 | 0.82 | MEN1 (0.40) | MEN1KMT2AKCNH2GRM5CYP1A2 | |
| SCHEMBL24981617 | 0.82 | KDM4E (0.39) | GPBAR1 | |
| SCHEMBL30121339 | 0.81 | MEN1 (0.44) | MEN1KMT2AKCNH2SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337203-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | Syndax Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022241265-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | SYNDAX PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | WO | disclosed |