Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359834 | 1.00 | CYP2A6 (0.39) | CYP2A6IRAK4AURKAMAP3K7FLT3 | |
| SCHEMBL10254559 | 0.75 | IRAK4 (0.40) | IRAK4AURKAMAP3K7FLT3SYK | |
| SCHEMBL30679394 | 0.72 | IRAK4 (0.37) | IRAK4AURKAMAP3K7FLT3SYK | |
| SCHEMBL21371622 | 0.72 | IRAK4 (0.37) | IRAK4AURKAMAP3K7FLT3SYK | |
| SCHEMBL657295 | 0.72 | IRAK4 (0.37) | IRAK4AURKAMAP3K7FLT3SYK | |
| SCHEMBL359942 | 0.71 | SYK (0.39) | CYP2A6SYK | |
| SCHEMBL29936180 | 0.71 | IRAK4 (0.39) | IRAK4AURKAMAP3K7FLT3SYK | |
| SCHEMBL360516 | 0.71 | IRAK4 (0.39) | IRAK4AURKAMAP3K7FLT3SYK | |
| SCHEMBL4302108 | 0.71 | IRAK4 (0.39) | IRAK4AURKAMAP3K7FLT3SYK | |
| SCHEMBL24375572 | 0.70 | IRAK4 (0.39) | IRAK4AURKAMAP3K7FLT3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-B | Morpholine derivative, and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |