Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SCD | O00767 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729290 | 1.00 | HSD17B10 (0.61) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL24729247 | 0.91 | HSD17B10 (0.50) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL29947476 | 0.91 | HSD17B10 (0.50) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL29947530 | 0.88 | HSD17B10 (0.72) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL24729462 | 0.88 | HSD17B10 (0.72) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL24729379 | 0.88 | HSD17B10 (0.59) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL29947463 | 0.88 | HSD17B10 (0.59) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL29947521 | 0.87 | HSD17B10 (0.67) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL24729401 | 0.87 | HSD17B10 (0.67) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 | |
| SCHEMBL24729394 | 0.86 | HSD17B10 (0.69) | HSD17B10HSD17B1HSD17B2LRRK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |