Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729471 | 1.00 | HSD17B10 (0.77) | HSD17B10MEN1POLBKMT2ARXFP1 | |
| SCHEMBL24729232 | 0.89 | HSD17B10 (0.82) | HSD17B10MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL29947688 | 0.86 | HSD17B10 (0.77) | HSD17B10MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL29947487 | 0.86 | HSD17B10 (0.64) | HSD17B10MEN1POLBKMT2ARXFP1 | |
| SCHEMBL24729258 | 0.86 | HSD17B10 (0.77) | HSD17B10MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL24729308 | 0.86 | HSD17B10 (0.64) | HSD17B10MEN1POLBKMT2ARXFP1 | |
| SCHEMBL29947383 | 0.85 | HSD17B10 (0.72) | HSD17B10MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL24729517 | 0.85 | HSD17B10 (0.72) | HSD17B10MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL24729511 | 0.85 | HSD17B10 (0.62) | HSD17B10MEN1POLBKMT2ARXFP1 | |
| SCHEMBL29947706 | 0.85 | HSD17B10 (0.62) | HSD17B10MEN1POLBKMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |