Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729281 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL24730610 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL29947502 | 0.91 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL29947538 | 0.88 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL24729428 | 0.88 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL24729291 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL29947501 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL29947579 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL693271 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL29947566 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | disclosed |