SCHEMBL29947749

SCHEMBL29947749

NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)NCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 1/20 0.40
▸ CTSC P53634 4/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ PRCP P42785 2/20 0.39
▸ CALCRL Q16602 1/20 0.38
▸ TERT O14746 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ HTR2C P28335 1/20 0.34
▸ HTR2B P41595 1/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ TLR2 O60603 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517049 0.88 DPP7 (0.41) DPP7CTSCMEN1KMT2APRCP
SCHEMBL31146508 0.86 DPP7 (0.43) DPP7CTSCMEN1KMT2APRCP
SCHEMBL29608892 0.86 DPP7 (0.42) DPP7CTSCMEN1KMT2APRCP
SCHEMBL27740315 0.85 PTGS1 (0.43) DPP7CTSCMEN1KMT2APRCP
SCHEMBL27740313 0.85 PTGS1 (0.43) DPP7CTSCMEN1KMT2APRCP
SCHEMBL30448973 0.84 MEN1 (0.46) DPP7CTSCMEN1KMT2APRCP
SCHEMBL27212654 0.84 MEN1 (0.46) DPP7CTSCMEN1KMT2APRCP
SCHEMBL27212749 0.84 MEN1 (0.46) DPP7CTSCMEN1KMT2APRCP
SCHEMBL29630616 0.84 MEN1 (0.41) DPP7CTSCMEN1KMT2APRCP
SCHEMBL8363914 0.84 CALCRL (0.42) DPP7CTSCMEN1KMT2APRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP claimed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US claimed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP claimed
CN-117355341-A TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases 纽约州立大学研究基金会 2024-01-05 — — CN claimed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO claimed
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP disclosed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US disclosed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP disclosed
CN-117355341-A TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases 纽约州立大学研究基金会 2024-01-05 — — CN disclosed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES TLR7, TLR8, TLR9 DPP7 1361/4885CTSC 1982/4885MEN1 4422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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