Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 1.00 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947698 | 0.99 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL29947769 | 0.98 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL29947608 | 0.92 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL29136637 | 0.90 | TLR7 (0.87) | TLR7 | |
| SCHEMBL26981137 | 0.89 | TLR7 (0.95) | TLR7TLR8 | |
| SCHEMBL26981083 | 0.88 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL15698491 | 0.87 | TLR7 (0.82) | TLR7TLR8 | |
| SCHEMBL29947776 | 0.87 | TLR7 (0.82) | TLR7TLR8 | |
| SCHEMBL29947632 | 0.86 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL27238484 | 0.86 | TLR7 (1.00) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301417-A1 | TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES | The Research Foundation for The State University of New York (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022187809-A1 | TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-09 | — | — | WO | disclosed |