Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138057 | 1.00 | HAVCR2 (0.49) | HAVCR2HSD17B10KDM4ECA12CA9 | |
| SCHEMBL4249802 | 0.81 | PDE3B (0.49) | HSD17B10KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL8137886 | 0.78 | CHEK1 (0.56) | CA12CA9ALDH1A1ADORA3LMNA | |
| SCHEMBL8136188 | 0.78 | FEN1 (0.51) | KDM4EALDH1A1FEN1HPGDLMNA | |
| SCHEMBL8137817 | 0.78 | CHEK1 (0.49) | HAVCR2CA12CA9CHEK1 | |
| SCHEMBL8137430 | 0.78 | HAVCR2 (0.53) | HAVCR2CA12CA9PARP1SMN1; SMN2 | |
| SCHEMBL8143260 | 0.78 | GPR17 (0.36) | HAVCR2CA12CA9PARP1GABRA1 | |
| SCHEMBL8134411 | 0.78 | PARP1 (0.45) | HAVCR2CA12CA9PARP1CHEK1 | |
| SCHEMBL8134451 | 0.78 | FEN1 (0.51) | KDM4EPARP1GABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL8137045 | 0.76 | PARP1 (0.44) | HAVCR2CA12CA9PARP1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752507-B1 | TRIAZOLOQUINAZOLINONE SYNTHESIS | GABATHER AB (SE) | 2022-11-16 | — | — | EP | claimed |