SCHEMBL29948547

SCHEMBL29948547

Nc1cc(NC(=O)[C@H]2[C@H](c3cc(Cl)cc(Cl)c3)C2(Cl)Cl)ccc1F

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.55
KMT2A Q03164 6/20 0.55
LMNA P02545 3/20 0.55
ALDH1A1 P00352 1/20 0.49
RECQL P46063 1/20 0.49
MAPT P10636 2/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.42
HTT P42858 4/20 0.40
HPGD P15428 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
FADS1 O60427 1/20 0.38
SLC9A1 P19634 1/20 0.37
MALT1 Q9UDY8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24731595 1.00 MEN1 (0.55) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL18146526 0.91 MEN1 (0.47) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL18146521 0.91 MEN1 (0.47) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL18146524 0.91 MEN1 (0.47) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL24731579 0.89 MEN1 (0.50) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL29948436 0.89 MEN1 (0.50) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL21021865 0.85 MEN1 (0.55) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL18148206 0.84 KMT2A (0.44) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL19442242 0.84 KMT2A (0.44) MEN1KMT2ALMNAALDH1A1RECQL
SCHEMBL18147779 0.83 MEN1 (0.46) MEN1KMT2ALMNAALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313939-A1 MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2024-02-07 EP disclosed
CN-117098750-A Molecules having pesticidal utility, and intermediates and methods related thereto 科迪华农业科技有限责任公司 2023-11-21 CN disclosed
WO-2022204080-A1 MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2022-09-29 WO disclosed