SCHEMBL29948560

SCHEMBL29948560

Cc1ccccc1C(=O)Nc1cc(NC(=O)[C@H]2[C@H](c3cc(Cl)cc(Cl)c3)C2(Cl)Cl)ccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
ALDH1A1 P00352 3/20 0.51
RECQL P46063 1/20 0.51
HTT P42858 3/20 0.48
LMNA P02545 3/20 0.47
MAPT P10636 3/20 0.47
HPGD P15428 2/20 0.47
MAPK1 P28482 1/20 0.47
DHODH Q02127 1/20 0.46
GRM4 Q14833 1/20 0.45
CYP2C9 P11712 1/20 0.45
KCNMA1 Q12791 1/20 0.44
PNLIP P16233 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24730131 1.00 MEN1 (0.51) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL24730126 0.91 MAPT (0.56) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL29948556 0.91 MAPT (0.56) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL24730086 0.88 KMT2A (0.51) MEN1KMT2AALDH1A1RECQLLMNA
SCHEMBL29948396 0.88 KMT2A (0.51) MEN1KMT2AALDH1A1RECQLLMNA
SCHEMBL18146469 0.88 MEN1 (0.51) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL18146466 0.88 MEN1 (0.51) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL18146465 0.88 MEN1 (0.51) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL24730236 0.88 MEN1 (0.48) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL29948438 0.88 MEN1 (0.48) MEN1KMT2AALDH1A1RECQLHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313939-A1 MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO Corteva Agriscience LLC (US) 2024-02-07 EP disclosed
WO-2022204080-A1 MOLECULES HAVING PESTICIDAL UTILITY AND INTERMEDIATES AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2022-09-29 WO disclosed