SCHEMBL29950607

SCHEMBL29950607

COC(=O)CNC(=O)c1ccc(B(O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
TSHR P16473 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HSD17B10 Q99714 1/20 0.55
GAA P10253 1/20 0.53
TRPV1 Q8NER1 3/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MAPK1 P28482 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
XDH P47989 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8947242 0.88 KMT2A (0.67) KDM4EMEN1KMT2ATSHRSMN1; SMN2
SCHEMBL17165865 0.86 NPC1 (0.63) KDM4EMEN1KMT2ASMN1; SMN2GAA
SCHEMBL2557121 0.84 PRSS1 (0.51) MEN1KMT2ASMN1; SMN2TRPV1ALDH1A1
SCHEMBL834861 0.81 KMT2A (0.59) KDM4EMEN1KMT2ATSHRSMN1; SMN2
SCHEMBL8150723 0.81 KDM4E (0.62) KDM4ETRPV1MAPK1
SCHEMBL24224262 0.81 KMT2A (0.59) KDM4EMEN1KMT2ATSHRSMN1; SMN2
SCHEMBL30838576 0.81 KDM4E (0.62) KDM4EMEN1KMT2ATSHRSMN1; SMN2
SCHEMBL8283407 0.81 TDP1 (0.71) KDM4EMEN1KMT2ATSHRSMN1; SMN2
SCHEMBL15358805 0.80 TRPV1 (0.55) KDM4EGAATRPV1
SCHEMBL1490749 0.80 HPGD (0.62) MEN1KMT2ASMN1; SMN2TRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737451-A1 NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Dong Wha Pharm. Co., Ltd. (KR) 2026-05-06 EP disclosed
WO-2025003988-A1 NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 동화약품주식회사 2025-01-02 WO disclosed
WO-2025003987-A1 NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 동화약품주식회사 2025-01-02 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed