Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079166 | 1.00 | MAPT (0.68) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL1079165 | 1.00 | MAPT (0.68) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL10384632 | 0.85 | MAPT (0.65) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL20517908 | 0.84 | MAPT (0.64) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL3462948 | 0.82 | MAPT (0.61) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL30478655 | 0.82 | MAPT (0.61) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL2491340 | 0.82 | MAPT (0.61) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL981600 | 0.81 | MAPT (1.00) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL12948682 | 0.81 | MAPT (1.00) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL11787354 | 0.80 | MAPT (0.59) | MAPTRAB9AMAPK1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |