SCHEMBL29951712

SCHEMBL29951712

NCC1(C(=O)O)CCOC1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31
CACNA2D1 P54289 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1971456 0.87 CYP2C19 (0.35) CYP2C19CYP4F2CYP4A11USP2ALDH1A1
SCHEMBL29952710 0.79 CYP2C19 (0.33) CYP2C19CYP4F2CYP4A11PPARG
SCHEMBL31716682 0.77 CYP4F2 (0.37) CYP2C19CYP4F2CYP4A11
SCHEMBL1527341 0.74
SCHEMBL8216989 0.74 KDM4E (0.34)
SCHEMBL28870918 0.73 CYP4F2 (0.35) CYP4F2CYP4A11USP2SMN1; SMN2
SCHEMBL12587392 0.72 SMN1; SMN2 (0.31) SMN1; SMN2
Hydrochloric Acid SCHEMBL5665222 0.72
SCHEMBL22070730 0.72 CYP4F2 (0.45) CYP4F2CYP4A11
SCHEMBL2029980 0.71 CYP2C19 (0.37) CYP2C19CYP4F2CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed