Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956510 | 0.83 | CA1 (0.52) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL1999038 | 0.83 | NOTUM (0.77) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL475762 | 0.83 | NOTUM (0.77) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL31144878 | 0.77 | NOTUM (0.68) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL15077172 | 0.77 | NOTUM (0.68) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL2159012 | 0.77 | NOTUM (0.68) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL3506718 | 0.77 | NOTUM (0.68) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL8506291 | 0.77 | NOTUM (0.68) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL31749401 | 0.77 | NOTUM (0.68) | NOTUMCES2CFTRCA12CA1 | |
| SCHEMBL630815 | 0.76 | NOTUM (0.66) | NOTUMCES2CFTRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |