Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3271716 | 1.00 | PDE10A (0.69) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL19287901 | 0.98 | PDE10A (0.67) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL7317281 | 0.83 | PDE10A (0.77) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL12066225 | 0.82 | PDE10A (1.00) | PDE10AMEN1KMT2AMAPT | |
| SCHEMBL7071801 | 0.80 | PDE10A (0.71) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL4677179 | 0.78 | PDE10A (0.69) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5247878 | 0.78 | PDE10A (0.69) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL17179177 | 0.78 | PDE10A (0.69) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5792272 | 0.78 | PDE10A (0.69) | PDE10AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL2646721 | 0.78 | PDE10A (0.69) | PDE10AMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |