Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330102 | 0.88 | MAPT (0.35) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL15332615 | 0.85 | MGAM (0.45) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL29956862 | 0.85 | ABCB1 (0.46) | SMN1; SMN2ABCB1HSD17B10MAPTL3MBTL1 | |
| SCHEMBL15330640 | 0.82 | KMT2A (0.46) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL15330506 | 0.82 | MAPT (0.40) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL2557296 | 0.81 | GRIN2D (0.41) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL15333338 | 0.81 | CYP19A1 (0.43) | SMN1; SMN2HSD17B10MAPTMAPK1ALDH1A1 | |
| SCHEMBL29957349 | 0.80 | ABCB1 (0.42) | SMN1; SMN2ABCB1MAPTALDH1A1KMT2A | |
| SCHEMBL2557662 | 0.80 | ABCB1 (0.42) | SMN1; SMN2GAAABCB1HSD17B10MAPT | |
| SCHEMBL15332936 | 0.79 | GAA (0.41) | SMN1; SMN2MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |