Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 6/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 7/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714533 | 1.00 | KMT2A (0.53) | KMT2APIM1CYP2A6IMPDH2ADORA2A | |
| SCHEMBL5263827 | 0.80 | KMT2A (0.54) | KMT2APIM1CYP2A6IMPDH2ADORA2A | |
| SCHEMBL29953043 | 0.79 | KMT2A (0.53) | KMT2ACYP2A6IMPDH2ADORA2AKDM4E | |
| SCHEMBL13132293 | 0.79 | KMT2A (0.53) | KMT2ACYP2A6IMPDH2ADORA2AKDM4E | |
| SCHEMBL23726193 | 0.78 | KMT2A (0.49) | KMT2APIM1CYP2A6IMPDH2ADORA2A | |
| SCHEMBL29659275 | 0.76 | ADORA2A (0.40) | PIM1ADORA2AKDM4EPIM3PIM2 | |
| SCHEMBL20455615 | 0.76 | ADORA2A (0.40) | PIM1ADORA2AKDM4EPIM3PIM2 | |
| SCHEMBL12460171 | 0.75 | PIM1 (0.37) | KMT2APIM1ADORA2APIM3PIM2 | |
| SCHEMBL14735522 | 0.75 | KMT2A (0.49) | KMT2APIM1CYP2A6IMPDH2CCNT1 | |
| SCHEMBL29955200 | 0.75 | KMT2A (0.49) | KMT2APIM1CYP2A6IMPDH2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |