Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729661 | 0.76 | CCR4 (0.39) | KDRLMNACREBBP | |
| SCHEMBL29664064 | 0.76 | CCR4 (0.39) | KDRLMNACREBBP | |
| SCHEMBL15011334 | 0.75 | CREBBP (0.34) | KDRCREBBP | |
| Hydrochloric Acid SCHEMBL29958115 | 0.75 | CCR4 (0.38) | KDRLMNACREBBP | |
| SCHEMBL29958362 | 0.75 | CREBBP (0.34) | KDRCREBBP | |
| SCHEMBL27228033 | 0.74 | ADORA2A (0.39) | KDRADORA2AADORA2BKDM4ELMNA | |
| SCHEMBL30861129 | 0.74 | ADORA2A (0.39) | KDRADORA2AADORA2BKDM4ELMNA | |
| SCHEMBL29955542 | 0.74 | ADORA2A (0.32) | ADORA2AADORA2BIDO1TDO2 | |
| SCHEMBL26581097 | 0.72 | KDM4E (0.44) | KDRKDM4EKMOKDM4CALDH1A1 | |
| SCHEMBL29704434 | 0.70 | CREBBP (0.34) | KDRCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |