Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PRF1 | P14222 | 5/20 | 0.49 |
| ▸ | GRM5 | P41594 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610013 | 1.00 | CA12 (0.50) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL2014718 | 0.86 | PRF1 (0.61) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL29950887 | 0.85 | CLK4 (0.53) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL26119392 | 0.85 | CLK4 (0.53) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL28697772 | 0.84 | PRF1 (0.51) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL2017969 | 0.82 | PRF1 (0.64) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL3946742 | 0.82 | PARP10 (0.60) | GRM5PARP1 | |
| SCHEMBL25042822 | 0.80 | PRF1 (0.45) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL618639 | 0.73 | CA12 (0.53) | CA12CA9PRF1GRM5GSK3B | |
| SCHEMBL164795 | 0.73 | GRM5 (0.68) | CA12CA9PRF1GRM5GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665332-A2 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | Differentiated Therapeutics Inc (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173412-A2 | CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF | DIFFERENTIATED THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |