Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548299 | 0.78 | KDM4E (0.53) | KDM4EPSMD14COPS5PARP1HSP90AA1 | |
| Jineol SCHEMBL29696064 | 0.77 | KDM4E (0.67) | KDM4EHSP90AA1HSP90AB1 | |
| Jineol SCHEMBL4213727 | 0.77 | KDM4E (0.67) | KDM4EHSP90AA1HSP90AB1 | |
| Jineol SCHEMBL28133873 | 0.76 | KDM4E (0.65) | KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL29956211 | 0.75 | HSP90AA1 (0.51) | KDM4EPSMD14COPS5HSP90AA1HSP90AB1 | |
| SCHEMBL31062026 | 0.74 | KDM4E (0.44) | KDM4EPSMD14COPS5PARP1HSP90AA1 | |
| SCHEMBL8489038 | 0.74 | KDM4E (0.44) | KDM4EPSMD14COPS5PARP1HSP90AA1 | |
| SCHEMBL12487794 | 0.74 | KDM4E (0.44) | KDM4EPSMD14COPS5PARP1HSP90AA1 | |
| SCHEMBL686920 | 0.74 | CCR1 (0.52) | KDM4EHSP90AA1HSP90AB1CCR1CCR5 | |
| SCHEMBL30570886 | 0.74 | CCR1 (0.52) | KDM4EHSP90AA1HSP90AB1CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |