SCHEMBL29952671

SCHEMBL29952671

O=Cc1c[nH]c2cc(O)ncc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 2/20 0.48
CDK9 P50750 2/20 0.48
HASPIN Q8TF76 2/20 0.48
CYP2A6 P11509 3/20 0.47
PLG P00747 1/20 0.45
PLAU P00749 1/20 0.45
IMPDH2 P12268 1/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.40
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950684 0.81 CCNT1 (0.49) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL16597854 0.79 CYP2A6 (0.56) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL29952670 0.79 CCNT1 (0.48) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL29955375 0.79 CYP2A6 (0.56) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL29952935 0.79 CCNT1 (0.48) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL23726991 0.79 CCNT1 (0.48) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL3033737 0.76 MAPT (0.55) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL29950941 0.76 CCNT1 (0.44) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL29958258 0.71 CYP2A6 (0.64) CCNT1CDK9HASPINCYP2A6PLG
SCHEMBL15324073 0.71 CYP2A6 (0.64) CCNT1CDK9HASPINCYP2A6PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed