Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | GPR183 | P32249 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177485 | 0.97 | HPGD (0.61) | SMN1; SMN2GPR183HPGDRXFP1ALDH1A1 | |
| SCHEMBL1490523 | 0.95 | HPGD (0.62) | SMN1; SMN2GPR183HPGDALDH1A1TP53 | |
| SCHEMBL20395747 | 0.95 | HPGD (0.62) | SMN1; SMN2GPR183HPGDALDH1A1TP53 | |
| SCHEMBL29957780 | 0.93 | GPR183 (0.64) | SMN1; SMN2GPR183HPGDRXFP1ALDH1A1 | |
| SCHEMBL8123 | 0.86 | TSHR (0.60) | GPR183HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL12538130 | 0.86 | GPR183 (0.54) | SMN1; SMN2GPR183HPGDALDH1A1TP53 | |
| SCHEMBL1367131 | 0.86 | GPR183 (0.57) | SMN1; SMN2GPR183HPGDALDH1A1TP53 | |
| SCHEMBL13022078 | 0.86 | GPR183 (0.54) | SMN1; SMN2GPR183HPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL17983620 | 0.84 | GPR183 (0.56) | SMN1; SMN2GPR183HPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL29664011 | 0.84 | GPR183 (0.56) | SMN1; SMN2GPR183HPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |