Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950969 | 0.84 | HTT (0.46) | HTTNCOA3KMT2AMEN1SLC22A12 | |
| SCHEMBL24212085 | 0.84 | HTT (0.46) | HTTNCOA3KMT2AMEN1SLC22A12 | |
| SCHEMBL29951381 | 0.82 | HDAC8 (0.38) | HTTKMT2AMEN1CCR1CCR5 | |
| SCHEMBL2978066 | 0.80 | HTT (0.46) | HTTNCOA3KMT2AMEN1SLC22A12 | |
| SCHEMBL13694776 | 0.77 | HTT (0.43) | HTTNCOA3KMT2AMEN1SLC22A12 | |
| SCHEMBL19171743 | 0.77 | CYP2A6 (0.35) | CCR1CCR5CCR8CCNT1CDK9 | |
| SCHEMBL2566365 | 0.74 | CYP2A6 (0.34) | CCR1CCR5CCR8CCNT1CDK9 | |
| SCHEMBL29955436 | 0.73 | KMT2A (0.46) | KMT2AMEN1CCR1CCR5CCR8 | |
| SCHEMBL2600757 | 0.73 | KMT2A (0.46) | KMT2AMEN1CCR1CCR5CCR8 | |
| SCHEMBL20043 | 0.73 | HTT (0.50) | HTTNCOA3KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |