Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560607 | 1.00 | NOTUM (0.48) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29957636 | 1.00 | NOTUM (0.48) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2560235 | 0.86 | KDM4E (0.62) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29950907 | 0.86 | KDM4E (0.62) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29953582 | 0.86 | KDM4E (0.62) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2560204 | 0.85 | NOTUM (0.59) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29952998 | 0.85 | NOTUM (0.59) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29955236 | 0.85 | NOTUM (0.59) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2555803 | 0.85 | GAA (0.57) | NOTUMGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL15330773 | 0.81 | NOTUM (0.57) | NOTUMKDM4EALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |