SCHEMBL29953263

SCHEMBL29953263

OB(O)c1ccc2c(C(F)F)cccc2c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
ENPP2 Q13822 6/20 0.37
PLG P00747 1/20 0.37
F12 P00748 1/20 0.37
F11 P03951 1/20 0.37
KLKB1 P03952 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
MGLL Q99685 2/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29951069 0.86 CA1 (0.48) CA1CA2ENPP2MGLLALDH1A1
SCHEMBL29952765 0.81 CA1 (0.46) CA1CA2ENPP2MGLLALDH1A1
SCHEMBL5778117 0.77 CA1 (0.53) CA1CA2ENPP2PLGF12
SCHEMBL29951741 0.77 CA1 (0.53) CA1CA2ENPP2PLGF12
SCHEMBL29956955 0.76 CA1 (0.44) CA1CA2ENPP2PLGF12
SCHEMBL29955900 0.74 CA1 (0.55) CA1CA2ENPP2KDM4ECYP1A2
SCHEMBL20600631 0.74 CA1 (0.55) CA1CA2ENPP2KDM4ECYP1A2
SCHEMBL24807948 0.73 CA1 (0.53) CA1CA2ENPP2PLGF12
SCHEMBL29950935 0.73 CA1 (0.53) CA1CA2ENPP2PLGF12
SCHEMBL29957738 0.73 CA1 (0.53) CA1CA2ENPP2PLGF12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed