Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 9/20 | 0.45 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513258 | 1.00 | NR1H2 (0.45) | NR1H2UBA6CCR9CA12CA9 | |
| SCHEMBL1497620 | 0.90 | NR1H2 (0.46) | NR1H2CA12CA9ALDH1A1STS | |
| SCHEMBL29955030 | 0.90 | NR1H2 (0.46) | NR1H2CA12CA9ALDH1A1STS | |
| SCHEMBL1030670 | 0.86 | KCNQ3 (0.39) | NR1H2CA12CA9 | |
| SCHEMBL12996827 | 0.86 | NR1H2 (0.43) | NR1H2UBA6CA12CA9ALDH1A1 | |
| SCHEMBL22272339 | 0.86 | NR1H2 (0.41) | NR1H2UBA6CCR9MTNR1AMTNR1B | |
| SCHEMBL12829958 | 0.84 | NR1H2 (0.47) | NR1H2CA12CA9CA2NR1H3 | |
| SCHEMBL29764547 | 0.84 | CA12 (0.41) | NR1H2UBA6CA12CA9NR1H3 | |
| SCHEMBL1622774 | 0.84 | CA12 (0.41) | NR1H2UBA6CA12CA9NR1H3 | |
| SCHEMBL29955923 | 0.84 | NR1H2 (0.43) | NR1H2CCR9CA12CA9NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225915-B | Imidazopyridine compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2023-03-07 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |