Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957556 | 0.80 | POLB (0.35) | POLBMAP4K4 | |
| SCHEMBL29951686 | 0.78 | MKNK1 (0.44) | POLBMAP4K4MKNK1MKNK2 | |
| SCHEMBL29955580 | 0.77 | POLB (0.37) | POLBMAP4K4MKNK1MKNK2RPS6KA5 | |
| SCHEMBL29958343 | 0.76 | ERN1 (0.35) | POLBMAP4K4MKNK1MKNK2 | |
| SCHEMBL29955833 | 0.76 | POLB (0.35) | POLB | |
| SCHEMBL29952128 | 0.75 | MCHR1 (0.39) | POLBPTPN1MCHR1 | |
| SCHEMBL7060307 | 0.74 | PDE4B (0.42) | POLB | |
| SCHEMBL29958451 | 0.73 | MAP4K4 (0.32) | POLBMAP4K4 | |
| SCHEMBL7704346 | 0.73 | PDE4D (0.41) | POLB | |
| SCHEMBL29952725 | 0.72 | KAT2B (0.45) | POLBMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |