Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956235 | 0.81 | FFAR4 (0.41) | KCNH2 | |
| SCHEMBL29954929 | 0.81 | FFAR4 (0.40) | KCNH2 | |
| SCHEMBL29955946 | 0.80 | FFAR4 (0.40) | KCNH2 | |
| SCHEMBL5343908 | 0.79 | MCHR1 (0.41) | FFAR2GRM5LRRK2GRM4KRAS | |
| SCHEMBL15086913 | 0.79 | LRRK2 (0.41) | GRM5LRRK2KRASSOS1 | |
| SCHEMBL23967036 | 0.79 | LRRK2 (0.39) | FFAR2GRM5LRRK2EGFRITK | |
| SCHEMBL23967190 | 0.79 | KCNH2 (0.37) | FFAR2GRM5LRRK2EGFRITK | |
| SCHEMBL5338247 | 0.79 | KCNH2 (0.37) | FFAR2GRM5LRRK2EGFRITK | |
| SCHEMBL25409208 | 0.75 | IRAK4 (0.41) | FFAR2SOS1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL20889905 | 0.75 | CHEK1 (0.38) | GRM5LRRK2KRASSOS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |