Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.34 |
| ▸ | ELOC | Q15369 | 1/20 | 0.34 |
| ▸ | ELOB | Q15370 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114816 | 1.00 | KDM4E (0.43) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL18885171 | 1.00 | KDM4E (0.43) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL16471902 | 0.88 | KDM4E (0.43) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL17522054 | 0.77 | KDM4E (0.47) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL68088 | 0.75 | KDM4E (0.48) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL20621433 | 0.73 | KDM4E (0.44) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL18878404 | 0.73 | KDM4E (0.44) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL13379167 | 0.71 | KDM4E (0.48) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL5315082 | 0.68 | KDM4E (0.40) | KDM4ELMNAHTTNPC1NPSR1 | |
| SCHEMBL5582485 | 0.68 | KDM4E (0.40) | KDM4ELMNAHTTNPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |