Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957772 | 0.89 | KAT2B (0.43) | KAT2BBAZ2BHRH3EPHX2RAF1 | |
| SCHEMBL29956935 | 0.82 | MAOB (0.44) | HRH3EPHX2FAAHHIF1APARP10 | |
| SCHEMBL29955096 | 0.81 | PARP10 (0.50) | HRH3HIF1APARP10ABL1ERN1 | |
| SCHEMBL29957646 | 0.81 | ERN1 (0.56) | ERN1 | |
| SCHEMBL29950762 | 0.77 | ERN1 (0.36) | HRH3PARP10ABL1ERN1 | |
| SCHEMBL29953161 | 0.76 | KAT2B (0.50) | KAT2BBAZ2B | |
| SCHEMBL28173271 | 0.76 | BRAF (0.49) | ERN1 | |
| SCHEMBL29958429 | 0.76 | SCD (0.38) | KAT2BBAZ2BHRH3EPHX2RAF1 | |
| SCHEMBL29957292 | 0.75 | KAT2B (0.52) | KAT2BBAZ2B | |
| SCHEMBL29952862 | 0.74 | MAOB (0.44) | EPHX2FAAHPARP10ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |