Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858800 | 1.00 | DYRK1A (0.47) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL2066975 | 0.84 | DYRK1A (0.43) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL24139848 | 0.82 | DYRK1A (0.50) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL16020299 | 0.82 | DYRK1A (0.50) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL19234753 | 0.81 | NAMPT (0.51) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL10264054 | 0.81 | DYRK1A (0.49) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL13999418 | 0.81 | DYRK1A (0.49) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL18041429 | 0.81 | DYRK1A (0.49) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL30827831 | 0.81 | DYRK1A (0.49) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A | |
| SCHEMBL13975437 | 0.81 | DYRK1A (0.49) | DYRK1ANAMPTCYP3A4L3MBTL1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |