Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355680 | 1.00 | KMT2A (0.46) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL4348528 | 0.82 | DYRK1A (0.41) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL4348525 | 0.82 | DYRK1A (0.41) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL23926473 | 0.78 | DYRK1A (0.44) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL31403578 | 0.78 | DYRK1A (0.44) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL30590799 | 0.78 | DYRK1A (0.44) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL15839995 | 0.78 | DYRK1A (0.44) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL21463510 | 0.78 | DYRK1A (0.44) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL21618377 | 0.78 | DYRK1A (0.44) | KMT2ADYRK1ADYRK1BMEN1PARP1 | |
| SCHEMBL30628638 | 0.78 | DYRK1A (0.47) | KMT2ADYRK1ADYRK1BMEN1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |