Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373553 | 0.79 | — | — | |
| SCHEMBL9428088 | 0.76 | HCAR2 (0.51) | TSHRRAB9AHCAR2 | |
| SCHEMBL22445250 | 0.75 | — | — | |
| SCHEMBL1206530 | 0.72 | DAO (0.38) | TSHRDAOKDM5ARAB9AMEN1 | |
| SCHEMBL1204721 | 0.72 | ATM (0.42) | TSHRDAOKDM5ARAB9AMEN1 | |
| SCHEMBL1041484 | 0.71 | — | — | |
| SCHEMBL20568376 | 0.71 | HCAR2 (0.48) | DAORAB9AMEN1KMT2AHCAR2 | |
| SCHEMBL29428236 | 0.71 | DYRK1A (0.41) | TSHRDAOKDM5ARAB9AMEN1 | |
| SCHEMBL19201524 | 0.69 | — | — | |
| SCHEMBL6366504 | 0.69 | HCAR2 (0.66) | DAOHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |