Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955534 | 0.86 | EPHX2 (0.43) | KCNH2KAT2BBAZ2BKDM4EMRGPRX1 | |
| SCHEMBL29952008 | 0.81 | KAT2B (0.59) | KAT2BBAZ2BMRGPRX1HRH1 | |
| SCHEMBL2486551 | 0.80 | KCNH2 (0.58) | MKNK1MKNK2KCNH2OPRK1KAT2B | |
| SCHEMBL29951686 | 0.78 | MKNK1 (0.44) | MKNK1MKNK2KCNH2PARP10IRAK4 | |
| SCHEMBL1432308 | 0.78 | MKNK1 (0.56) | MKNK1MKNK2KCNH2OPRK1KAT2B | |
| SCHEMBL29952128 | 0.78 | MCHR1 (0.39) | KAT2BBAZ2BHRH1 | |
| SCHEMBL29952660 | 0.76 | PARP10 (0.40) | MKNK1MKNK2KCNH2OPRK1KAT2B | |
| SCHEMBL29951166 | 0.76 | ERN1 (0.41) | MKNK1MKNK2KCNH2OPRK1KAT2B | |
| SCHEMBL20646728 | 0.75 | KCNH2 (0.53) | MKNK1MKNK2KCNH2OPRK1KAT2B | |
| SCHEMBL19151444 | 0.75 | KCNH2 (0.53) | MKNK1MKNK2KCNH2OPRK1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |