SCHEMBL29954047

SCHEMBL29954047

Cn1ccc2ccc(C=O)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 1.00
GPR183 P32249 1/20 0.40
PRKCI P41743 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 4/20 0.37
TSHR P16473 1/20 0.37
PIK3CB P42338 1/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 1/20 0.36
PTGS2 P35354 1/20 0.36
RAB9A P51151 1/20 0.36
TRIM24 O15164 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
ALDH1A3 P47895 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1125855 1.00 CYP2A6 (1.00) CYP2A6GPR183PRKCIL3MBTL1ALDH1A1
SCHEMBL1125942 0.85 CYP2A6 (1.00) CYP2A6PRKCIPIK3CB
SCHEMBL29569100 0.85 CYP2A6 (1.00) CYP2A6PRKCIPIK3CB
SCHEMBL18029032 0.81 CYP2A6 (0.68) CYP2A6GPR183PRKCIL3MBTL1ALDH1A1
SCHEMBL28018792 0.77 CYP2A6 (0.62) CYP2A6ALDH1A1TSHRKDM4EPTGS2
SCHEMBL757446 0.77 CYP2A6 (0.62) CYP2A6ALDH1A1TSHRKDM4EPTGS2
SCHEMBL29952158 0.77 CYP2A6 (0.62) CYP2A6ALDH1A1
SCHEMBL1126156 0.77 CYP2A6 (0.62) CYP2A6ALDH1A1
SCHEMBL2945804 0.76 CYP2A6 (0.61) CYP2A6GPR183ALDH1A1TSHRMAPT
SCHEMBL2945800 0.76 CYP2A6 (0.61) CYP2A6GPR183ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4482831-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS Satya Therapeutics, Inc. (US) 2025-01-01 EP disclosed
CN-118696034-A Novel bicyclic compounds as RAD51 inhibitors 萨提亚疗法股份有限公司 2024-09-24 CN disclosed
WO-2023161782-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYARX PHARMA INNOVATIONS PVT LTD (IN) 2023-08-31 WO disclosed
EP-4185586-A1 NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Chong Kun Dang Pharmaceutical Corp. (KR) 2023-05-31 EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed