Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656615 | 0.79 | IDO1 (0.65) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL932921 | 0.77 | IDO1 (0.62) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL3756416 | 0.77 | IDO1 (0.52) | IDO1SLC6A4LMNA | |
| SCHEMBL14157282 | 0.76 | IDO1 (0.61) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL257060 | 0.76 | IDO1 (0.61) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL24969799 | 0.76 | IDO1 (0.61) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL31731921 | 0.76 | IDO1 (0.61) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL14541391 | 0.76 | IDO1 (0.61) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL932893 | 0.76 | IDO1 (0.61) | IDO1PYCR1GPR84HTR3EHTR3B | |
| SCHEMBL120051 | 0.76 | IDO1 (0.61) | IDO1PYCR1GPR84HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |