Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738830 | 1.00 | CYP1A2 (0.57) | CYP1A2POLBKDM4ELMNACASP6 | |
| SCHEMBL16633528 | 0.89 | CYP1A2 (0.57) | CYP1A2POLBKDM4ELMNACASP6 | |
| SCHEMBL10329143 | 0.86 | CYP1A2 (0.55) | CYP1A2POLBKDM4ELMNACASP6 | |
| SCHEMBL29952790 | 0.86 | CYP1A2 (0.55) | CYP1A2POLBKDM4ELMNACASP6 | |
| SCHEMBL29951957 | 0.78 | CA1 (0.50) | KDM4ECA2CA1ENPP2TTR | |
| SCHEMBL23797442 | 0.77 | TTR (0.48) | CA2CA1ENPP2TTR | |
| SCHEMBL20600767 | 0.77 | CA1 (0.48) | CA2CA1ENPP2TTR | |
| SCHEMBL12419233 | 0.77 | CA1 (0.44) | POLBKDM4ECA2CA1ENPP2 | |
| SCHEMBL14484415 | 0.75 | CYP1A2 (0.42) | CYP1A2POLBKDM4ELMNACASP6 | |
| SCHEMBL22075308 | 0.74 | CYP1A2 (0.40) | CYP1A2POLBKDM4ELMNACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |