Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11164596 | 0.98 | TDP1 (0.37) | TDP1ALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL29950522 | 0.80 | TDP1 (0.34) | TDP1 | |
| SCHEMBL8698659 | 0.78 | GBA1 (0.34) | ALDH1A1RAB9ASMN1; SMN2GAAGBA1 | |
| SCHEMBL8699249 | 0.76 | GBA1 (0.37) | ALDH1A1RAB9ASMN1; SMN2GAAGBA1 | |
| SCHEMBL8699056 | 0.76 | GBA1 (0.37) | ALDH1A1RAB9ASMN1; SMN2GAAGBA1 | |
| SCHEMBL11336130 | 0.74 | GBA1 (0.36) | ALDH1A1RAB9ASMN1; SMN2GAAGBA1 | |
| SCHEMBL776553 | 0.73 | GBA1 (0.44) | ALDH1A1RAB9ASMN1; SMN2GAAGBA1 | |
| SCHEMBL8699223 | 0.73 | — | — | |
| SCHEMBL29951163 | 0.73 | KMT2A (0.35) | ALDH1A1RAB9ASMN1; SMN2GAAGBA1 | |
| SCHEMBL9719601 | 0.71 | GBA1 (0.34) | ALDH1A1RAB9ASMN1; SMN2GAAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |