Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070484 | 0.75 | HSD17B10 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL19448889 | 0.74 | DAO (0.60) | GRIA1GRIA2GRIA3GRIA4HSD17B10 | |
| SCHEMBL8872288 | 0.74 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8872485 | 0.73 | GRIN2D (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL17603468 | 0.73 | KDM4E (0.60) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL29951486 | 0.71 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4HSD17B10 | |
| SCHEMBL4106429 | 0.70 | DAO (0.60) | GRIA1GRIA2GRIA3GRIA4HSD17B10 | |
| SCHEMBL1306045 | 0.70 | KDM4E (0.53) | GRIA1GRIA2GRIA3GRIA4HSD17B10 | |
| SCHEMBL7195058 | 0.70 | NPC1 (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3267277 | 0.70 | RXFP1 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |