Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557467 | 1.00 | NOTUM (0.60) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL29955392 | 1.00 | NOTUM (0.60) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2557537 | 0.93 | NOTUM (0.70) | NOTUMFFAR1 | |
| SCHEMBL29952029 | 0.85 | NOTUM (0.44) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL29953020 | 0.85 | NOTUM (0.44) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2557970 | 0.85 | FFAR4 (0.53) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2558210 | 0.85 | NOTUM (0.44) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2556414 | 0.85 | NOTUM (0.58) | NOTUMHTR1AADRA1AADRA1B | |
| SCHEMBL15330773 | 0.83 | NOTUM (0.57) | NOTUMKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL29950827 | 0.83 | NOTUM (0.57) | NOTUMKDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |