Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360823 | 1.00 | ALPG (0.60) | ALPGTHRBKDM4EMAPK1MEN1 | |
| SCHEMBL6470647 | 0.80 | CSNK2A2 (0.44) | ALPGTHRBMEN1KMT2ACSNK2A2 | |
| SCHEMBL6470649 | 0.77 | CSNK2A2 (0.47) | ALPGTHRBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29954496 | 0.75 | ALPG (1.00) | ALPGTHRBKDM4EMAPK1MEN1 | |
| SCHEMBL13978669 | 0.74 | ALPG (0.68) | ALPGTHRBKDM4EMAPK1MEN1 | |
| SCHEMBL29952252 | 0.72 | PTPN1 (0.51) | ALPGTHRBKDM4EMAPK1MEN1 | |
| SCHEMBL29957041 | 0.72 | CSNK2A2 (0.45) | KDM4EMEN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL29951231 | 0.70 | ALPG (0.61) | ALPGTHRBKDM4EMAPK1MEN1 | |
| SCHEMBL5373635 | 0.68 | PTPN1 (0.54) | KDM4EMEN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL21623744 | 0.67 | CSNK2A2 (0.49) | THRBCSNK2A2CSNK2BCSNK2A1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |