Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553829 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDTSHRHTR2A | |
| SCHEMBL15331541 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1HPGDTSHRHTR2A | |
| SCHEMBL15332505 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HPGDTSHRHTR2A | |
| SCHEMBL15331689 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL29955936 | 0.82 | PTGDR2 (0.42) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL3936165 | 0.82 | TSHR (0.66) | SMN1; SMN2ALDH1A1HPGDTSHRHTR2A | |
| SCHEMBL15332582 | 0.82 | TSHR (0.66) | SMN1; SMN2ALDH1A1HPGDTSHRHTR2A | |
| SCHEMBL2558957 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDTSHRHTR2A | |
| SCHEMBL29955443 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL29956422 | 0.81 | KDM4E (0.58) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |