Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 4/20 | 0.52 |
| ▸ | RXRB | P28702 | 3/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330209 | 1.00 | MAP4K4 (0.57) | MAP4K4KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL15331027 | 0.90 | MRGPRX4 (0.61) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9082648 | 0.89 | NR4A2 (0.54) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL16585825 | 0.89 | MAPT (0.60) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL16321220 | 0.85 | MAP4K4 (0.67) | MAP4K4MAPTKMT2AMEN1PTGER1 | |
| SCHEMBL930474 | 0.82 | MRGPRX4 (0.55) | KDM4EALDH1A1MAPTKMT2AMRGPRX4 | |
| SCHEMBL6341223 | 0.82 | KMT2A (0.66) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL29953305 | 0.82 | KMT2A (0.66) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5749968 | 0.81 | NR4A2 (0.54) | MAP4K4KMT2AMEN1PTGER1MRGPRX4 | |
| SCHEMBL2066161 | 0.81 | PTP4A3 (0.62) | KDM4EALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |