Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953327 | 0.88 | PARP1 (0.63) | PARP1PARP2HTTLMNAALOX15 | |
| SCHEMBL2558999 | 0.85 | PARP1 (0.60) | PARP1PARP2HTTLMNAALOX15 | |
| SCHEMBL29957144 | 0.84 | PARP1 (0.42) | PARP1PARP2HTTLMNAALOX15 | |
| SCHEMBL29955619 | 0.79 | PARP1 (0.58) | PARP1PARP2HTTLMNACREBBP | |
| SCHEMBL20468587 | 0.79 | PARP1 (0.58) | PARP1PARP2HTTLMNACREBBP | |
| SCHEMBL805483 | 0.79 | PARP1 (0.51) | PARP1PARP2HTTLMNAALOX15 | |
| SCHEMBL805487 | 0.78 | PARP1 (0.47) | PARP1PARP2HTTLMNAALOX15 | |
| SCHEMBL11956536 | 0.78 | PARP1 (0.47) | PARP1PARP2HTTLMNAALOX15 | |
| SCHEMBL12714306 | 0.78 | PARP1 (0.50) | PARP1PARP2HTTLMNAALOX15 | |
| SCHEMBL17212040 | 0.78 | PARP1 (0.47) | PARP1PARP2HTTLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |